Poštovani članovi,
Prosleđujemo vam informaciju o predstojećem vebinaru „Fiziologija astrocita“ u organizaciji Mediteranskog društva za neuronauke.
Predavanje će održati prof. Aleksej Verkhratski (Alexei Verkhratsky),
Univerzitet u Mančesteru, Ujedinjeno Kraljevstvo.
️ Petak, 19. decembar u 15:00 časova (CET)
Link za pristup: https://meet.google.com/drg-obkp-mup
The integration and information processing in the brain occurs though close interactions of two cellular circuits represented by neuronal networks embedded into internally connected astroglial syncytia. Our understanding of glial function changed dramatically over last two decades. This change concerns the whole concept of how the brain is organized, and how the development, life and death of neural circuits are controlled. There is compelling evidence demonstrating that these are the astrocytes that are creating the compartmentalisation in the CNS, and these are the astrocytes that are able to integrate neurones, synapses, and brain capillaries into individual and relatively independent units. Astroglial syncytia allow intercellular communication routes, which permit translocation of ions, metabolic factors and second messengers. The resulting potential for parallel processing and integration is significant and might easily be larger, but also fuzzier, than the binary coded electrical communication within the neuronal networks. The neuronal-glial circuitry endowed with distinct signalling cascades, form a "diffuse nervous net" suggested by Golgi, where millions of synapses belonging to very different neurones are integrated first into neuronal-glial-vascular units and then into more complex structures connected through glial syncytia. These many levels of integration, both morphological and functional, presented by
neuronal-glial circuitry ensure the spatial and temporal multiplication of brain cognitive power.
Srdačno,
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